Efficient operation of bioinformatics cores in the era of single cell omics

The SciLifeLab and its bioinformatics infrastructure NBIS are pioneering the analytical and computational methods to explore life at single cell resolution. The breadth and depth of this type of data type requires the establishment of new analysis workflows that are challenging on the algorithm side as well as on the computational resource side.

Life-cycle long data management and handling of sensitive data

The roadmap of the Institut Français de Bioinformatique (IFB, ELIXIR-FR) includes several actions that are tightly related to data management: storage, secure access, FAIRification, DMPs. However, France is facing many challenges to answer an increasing demands of our user communities. One of the most important bottlenecks in the French context concerns the access to and FAIRification of sensitive biomedical data, in order to enable its exploitation for research and transnational projects.

Transfer and development of cancer sequencing data analysis to Faculty of medicine in Pilsen, Charles University with focus on single cells

The purpose of this project is to train one postdoc researcher from Czech Republic in methodologies of sequencing data analysis from human cancers with focus on single cell sequencing datasets.

The project has two particular goals. The first goal of this training is initiation of building local capacity for analysis of such data produced in Faculty of Medicine in Pilsen, Charles University which is a part of the ELIXIR-CZ node. The second goal is to establish long-term collaboration between Charles University and Imperial College London.

LEAP - Linking Expertise and Analysis in Pathways

Reactome is a world-leading, curated resource for biomolecular pathways, with >1,200 citations in 2019 and >80,000 distinct users monthly. It is developed in international collaboration with EMBL-EBI as one of four partners. Reactome’s content is presented through a multi-scale visualisation system, complemented by advanced analysis tools. Beyond scientific analysis, Reactome is uniquely suited for teaching and training in molecular biology as well as in bioinformatics, through its open source, open data policy.

FAIRDOM

FAIRDOM, based on the SEEK platform by the group of Carole Goble and the group of Wolfgang Müller, is used by multiple Nodes in ELIXIR as data management platform.