Weekly Brief, 22 May 2023

This week's highlights

NIH ODSS/ELIXIR track programme in ISMB/ECCB 2023

23-27 July 2023 | Lyon, France

ISMB/ECCB brings together scientists from computer science, molecular biology, mathematics, statistics and related fields focusing on advanced computational methods for biological problems. This year, ELIXIR will have a track programme focusing on FAIR for Data Infrastructures in collaboration with NIH ODSS.

More information and registration

35 projects have been selected for BioHackathon 2023

The BioHackathon Programme Committee has selected 35 projects out of 80 eligible submitted projects. It was a tough decision for the Programme Committee since all projects submitted were of great quality.
More details on projects and registration will be announced soon. Thank you to all submitters and we look forward to seeing you in November!

Check the list of selected projects

Show & Tell: Analysing qualitative data & Measuring policy impact

26 May 2023 | 11:00 CEST

This additional Show and Tell will cover two topics:

  • Analysing qualitative data (using Nvivo) by Mariana de Freitas (ELIXIR Portugal)
  • Measuring policy impact (Overton.io demo) by Corinne Martin (ELIXIR Hub)

This event is part of the ELIXIR Strategic Implementation Study on Impact, in collaboration with ELIXIR-CONVERGE WP4. All participants are welcome to join, especially those involved in ELIXIR and interested in impact evaluation.

Register now

Recommended reads

Extending inherited metabolic disorder diagnostics with biomarker interaction visualizations

An EJP RD paper


Inherited Metabolic Disorders are rare diseases where one impaired protein leads to a cascade of changes in the adjacent chemical conversions. IMDs often present with non-specific symptoms, a lack of a clear genotypephenotype correlation, and de novo mutations, complicating diagnosis. Visualization of the connections between metabolic biomarkers and the enzymes involved might aid in the diagnostic process. The goal of this study was to provide a proof-of-concept framework for integrating knowledge of metabolic interactions with real-life patient data before scaling up this approach. This framework was tested on two groups of well-studied and related metabolic pathways. The lessons learned from the approach will help to scale up the framework and support the diagnosis of other less-understood IMDs.

Read more

Therapeutic Potential of Tumor Metabolic Reprogramming in Triple-Negative Breast Cancer


An ELIXIR-HU paper


Triple-negative breast cancer is the most aggressive subtype of breast cancer. It is characterized by genomic and transcriptional heterogeneity and a tumor microenvironment with the presence of high levels of stromal tumor-infiltrating lymphocytes, immunogenicity, and an important immunosuppressive landscape. A better understanding of the interaction between the TME and tumor cells, and the underlying molecular mechanisms of cell-cell communication signaling, may uncover additional targets for better therapeutic strategies in TNBC treatment. In this review, the authors aim to discuss the mechanisms in tumor metabolic reprogramming, linking these changes to potential targetable molecular mechanisms to generate new, physical science-inspired clinical translational insights for the cure of TNBC.

Read more

Updates from Nodes

Fellowship of the Data RDM trainers network meeting

21-22 June 2023 | Berlin, Germany

The RDM trainers network meeting provides opportunities for exchange and exploration along with a poster session as well as keynotes chosen to instigate further reflection and networking.

More information and registration

Call for project proposal: 2nd BioHackathon Germany

Deadline: 30 June 2023

After the successful 1st BioHackathon Germany, ELIXIR Germany and de.NBI are organising the 2nd BioHackathon Germany from 11-15 December 2023 in Bielefeld, Germany. Call for project proposal for BioHackathon Germany is now open, the proposals need to be aligned to challenges proposed by de.NBI / ELIXIR Germany and their service centers and units.

More information and project submission

Introducing FAIR Pointers, a course to embed FAIR data into the Life Sciences

A new training course, FAIR Pointers, co-written with ELIXIR-UK members and Fellows is now available. It is a short online course aims to introduce FAIR concepts and principles with signposting to FAIRresouces to those with little or no experience around FAIR data.

Read the news

Updates from Communities

Register for the IDP Community F2F/hybrid meeting

3-4 July 2023 | Hybrid - Bratislava, Slovakia
Registration deadline: 29 May (in person) | 04 July (online)

The IDP Community F2F/hybrid meeting aims to unite experimentalists and method developers to discuss challenges and define joint opportunities in the field. A part of the meeting will be dedicated to the 2024-2028 Scientific Programme and the Community's possible role and activities.

The meeting will be held before the COST Action ML4NG Main Conference (July 4-7)

Find out more and register now

Single-Cell Omics (SCO) Training Survey

Deadline: 30 June 2023

The survey, organised by the ELIXIR Single-Cell Omics Community, aims to understand the current training efforts in the field of single-cell omics, collect information on training materials and identify areas or technologies that lack training materials.

Fill out the survey

Survey to identify activities relevant for RD research across ELIXIR Nodes, Platforms and Communities

Deadline: 4 June 2023

ELIXIR Rare Disease Community is conducting a survey with the aim to identify existing infrastructures, resources and initiatives from ELIXIR Platforms, Communities and Focus Groups useful for the rare disease community

Fill out the survey

Updates from other initiatives

European Research Services on Agroecology Conference

5 & 6 June 2023 | Hybrid - Prague, Czech Republic


The first edition of the AgroServ Conference will be devoted to the research community where it will present the diverse agroecological services accessible via AgroServ and the different facets that shape research in the emerging field of agroecology.

More information and registration

Call for manuscripts on FAIR resources in biodiversity for special issue of Biodiversity Data Journal


BiCIKL will support free of charge publications submitted to the dedicated topical collection Linking FAIR biodiversity data through publications: The BiCIKL approach in the Biodiversity Data Journal. Manuscripts should demonstrate how biodiversity scientists can use various types of FAIR biodiversity data interlinked across databases and domains.

More information

BY-COVID Policy Brief: Open data to support European pandemic preparedness


The BY-COVID project has published a policy brief, Open data to support European pandemic preparedness, summarising learnings and policy recommendations to support pandemic preparedness.

Find out more

EUCANCan Workshop: Bridging the gap between research and clinical practice

24 May 2023 | 14:00-17:40 CEST | Online

This workshop hosted by EUCANCan aims to discuss what would be needed to bridge the gap between clinical practice and bioinformatics research to allow for joining forces.

More information and registration

Initial release of SCIENCE-CLUSTERS.EU website


The first version of a new website has been released showcasing cross-domain research infrastructure collaboration for open science.

Explore the website

Upcoming ELIXIR events & webinars

ELIXIR Training Courses & Webinars

The ELIXIR TeSS portal has a variety of interesting events and courses organised by the ELIXIR Nodes. For more, visit TeSS portal

PerMedCoE webinar: Utilising GPUs in scientific algorithms
15 June 2023 | 15:00 -16:00 CEST | Prague, Czech Republic


SIB course: Introduction to Statistics with Python
20-21 June 2023 | Basel, Switzerland


SIB course: Enrichment Analysis
23 June 2023 | Online

BioSB course: Algorithms for Biomolecular Networks
26-30 June 2023 | Wageningen, the Netherlands


SIB course: Introduction to openBIS
27 June 2023 | Online

SIB course: Introduction to FAIR Research Data Management & Data Management Plan
29-30 June 2023 | Lausanne, Switzerland

SIB course: Single-cell Transcriptomics
3-5 July 2023 | Bern, Switzerland


de.NBI Spring School: Big Data Analysis for Life Sciences
25-29 September 2023 | Bielefeld, Germany

ELIXIR Events and Conferences


ELIXIR All Hands 2023
5-8 June 2023 | Dublin, Ireland

IDP Community F2F/hybrid Meeting
3-4 July 2023 | Hybrid - Bratislava, Slovakia

BioHackathon Europe 2023
30 October - 3 November 2023 | Barcelona, Spain

Job vacancies

All vacancies are also published on the ELIXIR website (also including those from industry). If you need our help communicating your new open positions, you can submit a job advertisement and it will automatically appear on our newsletters. Go to our vacancy page to submit a job
 

Fixed-term technical position: Services based on machine and deep learning methodologies for the analysis of biological sequences and structures

Biocomputing group - University of Bologna

Fixed-term technical position: Interoperability services for biomedical data

Biocomputing group - University of Bologna

SILVA - Scientist Microbial Ecology & Taxonomy

DSMZ

SILVA - Backend developer Maven / Spring Boot

Leibniz Institute DSMZ

BRENDA - Data Expert Biochemistry/Enzymology

Leibniz Institute DSMZ